A screenshot from Akili's video game, designed to treat ADHD. Courtesy of Akili Interactive Labs Akili Interactive Labs has been working on a video game designed to treat children with ADHD. 348 kids diagnosed with ADHD participated in a study that involved played the game over a period of four weeks. Researchers noted a significant improvement in the children's attention span and inhibitory control. Akili plans to seek FDA approval next year. Akili Interactive Labs on Monday reported that its late-stage study of a video game designed to treat kids with ADHD met its primary goal, a big step in the Boston company’s quest to get approval for what it hopes will be the first prescription video game. In a study of 348 children between the ages of 8 and 12 diagnosed with ADHD, those who played Akili’s action-packed game on a tablet over four weeks saw statistically significant improvements on metrics of attention and inhibitory control, compared to children who were given a different action-driven video game designed as a placebo. The company plans next year to file for approval with the Food and Drug Administration. "We are directly targeting the key neurological pathways that control attention and impulsivity," said Akili CEO Eddie Martucci. The study "was meant to be a strong objective test to ask: Is it the targeting we do in the brain or is it general engagement with a treatment that’s exciting and interesting … that actually leads to these targeted effects? And so I think we clearly see that it’s the targeted algorithms that we have." Despite the positive results, questions about the product remain. For instance, parents and physicians perceived about the same amount of improvement in children’s behavior whether they were playing the placebo game or the therapeutic game. And if Akili can get approval, it remains to be seen whether clinicians and insurers will embrace its product. The video game has not been tested head-to-head against ADHD medications or psychotherapy to see if it’s equally effective. Akili’s video game, which is played on a tablet, sends players down a molten lava river and through an icy winter wonderland, rewarding them with